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中华产科急救电子杂志 ›› 2022, Vol. 11 ›› Issue (04) : 208 -212. doi: 10.3877/cma.j.issn.2095-3259.2022.04.004

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妊娠期地中海贫血的筛查与诊断
陈晓丹1, 侯红瑛1,()   
  1. 1. 510000 广州,中山大学附属第三医院产科
  • 收稿日期:2022-07-21 出版日期:2022-11-18
  • 通信作者: 侯红瑛

Screen and diagnosis of thalassemia

Xiaodan Chen1, Hongying Hou1()   

  • Received:2022-07-21 Published:2022-11-18
  • Corresponding author: Hongying Hou
引用本文:

陈晓丹, 侯红瑛. 妊娠期地中海贫血的筛查与诊断[J/OL]. 中华产科急救电子杂志, 2022, 11(04): 208-212.

Xiaodan Chen, Hongying Hou. Screen and diagnosis of thalassemia[J/OL]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2022, 11(04): 208-212.

地中海贫血是由于珠蛋白基因发生突变或者缺失引起的遗传性溶血性贫血。患地中海贫血的孕产妇发生与贫血相关的不良妊娠结局风险增加,如何有效对孕产妇进行地中海贫血筛查、诊断以及产前诊断是产科工作者的研究重点。本文根据近年来的指南、研究及实践经验,对妊娠期地中海贫血的筛查与诊断问题进行阐述。

Thalassemia is a hereditary hemolytic anemia caused by mutations or deletions in the globin gene. Women with thalassemia are at increased risk of adverse pregnancy outcomes associated with anemia. How to effectively screen and diagnose thalassemia play a key role in the management of thalassemia and has been widely studied nowadays. Based on clinical guidelines, literature research and practical experience in recent years, this paper discusses the screening strategies and diagnosis of thalassemia.

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