| [1] |
中华医学会血液学分会血栓与止血学组. 易栓症诊断与防治中国指南(2021年版)[J]. 中华血液学杂志，2021，42(11)：881-888.
|
| [2] |
Lefkou E, Parmar K, Mamopoulos A, et al. Peripartum Haemostatic Changes in Women in Labour[J]. Blood，2008，112(11)：1-2.
|
| [3] |
American College of Obstetricians and Gynecologists′ Committee on Practice Bulletins-Obstetrics. ACOG practice bulletin No. 197: inherited thrombophilias in pregnancy[J]. Obstet Gynecol，2018，132(1)：e18-e34.
|
| [4] |
Herrmann FH, Koesling M, Schrǒder W, et al. Prevalence of factor V Leiden mutation in various populations[J]. Genet Epidemiol，1997，14(4)：403-411.
|
| [5] |
Tam WH, Ng MH, Yiu AK, et al. Thrombophilia among Chinese women with venous thromboembolism during pregnancy[J]. Gynecol Obstet Invest，2012，73 (3)：183-188.
|
| [6] |
Shen MC, Lin JS, Tsay W. High prevalence of antithrombin Ⅲ，protein C and protein S deficiency, but no factor V Leiden mutation in venous thrombophilic Chinese patients in Taiwan[J]. Thromb Res，1997，87 (4)：377-385.
|
| [7] |
Stenflo J. A new vitamin K-dependent protein: purification from bovine plasma and preliminary characterization[J]. J Biol Chem，1976，251(2)：355-363.
|
| [8] |
Dinarvand P, Moser KA. Protein C deficiency[J]. Arch Pathol Lab Med，2019，143(10)：1281-1285.
|
| [9] |
Di Scipio RG, Hermodson MA, Yates SG, et al. A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S[J]. Biochemistry，1977，16(4)：698-706.
|
| [10] |
Gierula M, Ahnström J. Anticoagulant protein S-New insights on interactions and functions[J]. J Thromb Haemost，2020，18 (11)：2801-2811.
|
| [11] |
中华医学会围产医学分会. 产科抗磷脂综合征诊断与处理专家共识[J]. 中华围产医学杂志，2020，23(8)：517-522.
|
| [12] |
Esteve-Valverde E, Ferrer-Oliveras R, Alijotas-Reig J. Obstetric antiphospholipid syndrome[J]. Rev Clin Esp，2015，216(3)：135-145.
|
| [13] |
Knight JS, Kanthi Y. Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome[J]. Semin Immunopathol，2022，44 (3)：347-362.
|
| [14] |
Cervera R, Serrano R, Pons-Estel GJ, et al. Morbidity and mortality in the antiphospholipid syndrome during a 10-year period: a multicentre prospective study of 1000 patients[J]. Ann Rheum Dis，2015，74 (6)：1011-1018.
|
| [15] |
Jørgensen M, Broholm R, Bækgaard N. Pregnancy after catheter-directed thrombolysis for acute iliofemoral deep venous thrombosis[J]. Phlebology，2013，28 Suppl 1：34-38.
|
| [16] |
Antovic A, Bruzelius M. Impaired fibrinolysis in the antiphospholipid syndrome[J]. Semin Thromb Hemost，2021，47(5)：506-511.
|
| [17] |
Zhang W, Gao F, Lu D, et al. Anti-β2 glycoproteinⅠantibodies in complex with β2 glycoproteinⅠinduce platelet activation via two receptors: apolipoprotein E receptor 2′ and glycoproteinⅠbα[J]. Front Med，2016，10(1)：76-84.
|
| [18] |
Bondanza A, Sabbadini MG, Pellegatta F, et al. Anti-β2 glycoproteinⅠantibodies prevent the De-activation of platelets and sustain their phagocytic clearance[J]. J Autoimmun，2000，15(4)：469-477.
|
| [19] |
Engelmann B, Massberg S. Thrombosis as an intravascular effector of innate immunity[J]. Nat Rev Immunol，2013，13(1)：34-45.
|
| [20] |
Tambralli A, Gockman K, Knight JS. NETs in APS: current knowledge and future perspectives[J]. Curr Rheumatol Rep，2020，22(10)：1-12.
|
| [21] |
Yalavarthi S, Gould TJ, Rao AN, et al. Release of neutrophil extracellular traps by neutrophils stimulated with antiphospholipid antibodies: a newly identified mechanism of thrombosis in the antiphospholipid syndrome[J]. Arthritis Rheumatol，2015，67 (11)：2990-3003.
|
| [22] |
Sule G, Kelley WJ, Gockman K, et al. Increased adhesive potential of antiphospholipid syndrome neutrophils mediated by beta-2 integrin Mac-1[J]. Arthritis Rheumatol，2020，72(1)：114-124.
|
| [23] |
Branch DW, Dudley DJ, Mitchell MD, et al. Immunoglobulin G fractions from patients with antiphospholipid antibodies cause fetal death in BALB/c mice: a model for autoimmune fetal loss[J]. Am J Obstet Gynecol，1990，163(1 Pt 1)：210-216.
|
| [24] |
Oku K, Atsumi T, Bohgaki M, et al. Complement activation in patients with primary antiphospholipid syndrome[J]. Ann Rheum Dis，2009，68(6)：1030-1035.
|
| [25] |
Ritis K, Doumas M, Mastellos D, et al. A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways[J]. J Immunol，2006，177(7)：4794-4802.
|
| [26] |
Wolberg AS, Roubey RA. Mechanisms of autoantibody-induced monocyte tissue factor expression[J]. Thromb Res，2004，114(5-6)：391-396.
|
| [27] |
Müller-Calleja N, Ritter S, Hollerbach A, et al. Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies[J]. Blood Adv，2018，2(9)：979-986.
|
| [28] |
Sciascia S, Amigo MC, Roccatello D, et al. Diagnosing antiphospholipid syndrome: 'extra-criteria’ manifestations and technical advances[J]. Nat Rev Rheumatol，2017，13(9)：548-560.
|
| [29] |
Di Simone N, Meroni PL, de Papa N, et al. Antiphospholipid antibodies affect trophoblast gonadotropin secretion and invasiveness by binding directly and through adhered β2-glycoproteinⅠ[J]. Arthritis Rheum，2000，43(1)：140-150.
|
| [30] |
Carroll TY, Mulla MJ, Han CS, et al. Modulation of trophoblast angiogenic factor secretion by antiphospholipid antibodies is not reversed by heparin[J]. Am J Reprod Immunol，2011，66(4)：286-296.
|
| [31] |
Di Simone N, Di Nicuolo F, D′Ippolito S, et al. Antiphospholipid antibodies affect human endometrial angiogenesis[J]. Biol Reprod，2010，83(2)：212-219.
|
| [32] |
Quenby S, Mountfield S, Cartwright JE, et al. Antiphospholipid antibodies prevent extravillous trophoblast differentiation[J]. Fertil Steril，2005，83(3)：691-698.
|
| [33] |
Mulla MJ, Brosens JJ, Chamley LW, et al. Antiphospholipid antibodies induce a pro-inflammatory response in first trimester trophoblast via the TLR4/MyD88 pathway[J]. Am J Reprod Immunol，2009，62(2)：96-111.
|
| [34] |
Gysler SM, Mulla MJ, Guerra M, et al. Antiphospholipid antibody-induced miR-146a-3p drives trophoblast interleukin-8 secretion through activation of Toll-like receptor 8[J]. Mol Hum Reprod，2016，22(7)：465-474.
|
| [35] |
Mulla MJ, Weel IC, Potter JA, et al. Antiphospholipid antibodies inhibit trophoblast Toll-like receptor and inflammasome negative regulators[J]. Arthritis Rheumatol，2018，70(6)：891-902.
|
| [36] |
Ramesh S, Morrell CN, Tarango C, et al. Antiphospholipid antibodies promote leukocyte-endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2[J]. J Clin Invest，2010，121(1)：120-131.
|
| [37] |
Kim MY, Guerra MM, Kaplowitz E, et al. Complement activation predicts adverse pregnancy outcome in patients with systemic lupus erythematosus and/or antiphospholipid antibodies[J]. Ann Rheum Dis，2018，7(4)：549-555.
|
| [38] |
Cohen D, Buurma A, Goemaere NN, et al. Classical complement activation as a footprint for murine and human antiphospholipid antibody-induced fetal loss[J]. J Pathol，2011，225(4)：502-511.
|
| [39] |
Holers VM, Girardi G, Mo L, et al. Complement C3 activation is required for antiphospholipid antibody-induced fetal loss[J]. J Exp Med，2002，195(2)：211-220.
|
| [40] |
Girardi G, Berman J, Redecha P, et al. Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome[J]. J Clin Invest，2003，112(11)：1644-1654.
|
| [41] |
Marder W, Knight JS, Kaplan MJ, et al. Placental histology and neutrophil extracellular traps in lupus and pre-eclampsia pregnancies[J]. Lupus Sci Med，2016，3(1)：1-9.
|
| [42] |
Lu Y, Dong Y, Zhang Y, et al. Antiphospholipid antibody-activated NETs exacerbate trophoblast and endothelial cell injury in obstetric antiphospholipid syndrome[J]. J Cell Mol Med，2020，24(12)：6690-6703.
|