切换至 "中华医学电子期刊资源库"

中华产科急救电子杂志 ›› 2023, Vol. 12 ›› Issue (04) : 228 -231. doi: 10.3877/cma.j.issn.2095-3259.2023.04.008

妊娠合并内分泌疾病

妊娠合并嗜铬细胞瘤的诊治
刘燕燕, 曾万江()   
  1. 430030 武汉,华中科技大学同济医学院附属同济医院妇产科
  • 收稿日期:2023-07-22 出版日期:2023-11-18
  • 通信作者: 曾万江
  • 基金资助:
    湖北省卫生健康委员会面上项目(WJ2023M022); 湖北省自然科学基金计划项目(2023AFB892)

Diagnosis and treatment of pheochromocytoma in pregnancy

Yanyan Liu, Wanjiang Zeng()   

  • Received:2023-07-22 Published:2023-11-18
  • Corresponding author: Wanjiang Zeng
引用本文:

刘燕燕, 曾万江. 妊娠合并嗜铬细胞瘤的诊治[J]. 中华产科急救电子杂志, 2023, 12(04): 228-231.

Yanyan Liu, Wanjiang Zeng. Diagnosis and treatment of pheochromocytoma in pregnancy[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2023, 12(04): 228-231.

妊娠合并嗜铬细胞瘤是一种罕见但危险的内分泌肿瘤,典型临床表现包括阵发性或持续性高血压,严重时危及生命。该疾病可引起胎儿生长受限、胎盘早剥等产科并发症,诊断和管理的关键在于综合分析临床症状、实验室检查和利用影像学技术进行早期诊断;肾上腺切除术是首选治疗方法,随访和监测对于预防并发症和疾病复发至关重要。进一步的研究和临床经验积累将有助于我们更深入地理解和管理该疾病。

Pheochromocytoma in pregnancy is a rare but dangerous endocrine tumor. Typical clinical manifestations include paroxysmal or persistent hypertension, which can be life-threatening in severe cases. This disease can cause obstetric complications such as fetal growth restriction and placental abruption. The key to diagnosis and management lies in the comprehensive use of clinical symptoms, laboratory examinations, and imaging techniques for early diagnosis. Adrenalectomy is the preferred treatment method. Follow-up and monitoring are crucial for preventing complications and recurrence. Further research and experience accumulation will help us gain a deeper understanding and management of this disease.

[1]
中华医学会内分泌学分会. 嗜铬细胞瘤和副神经节瘤诊断治疗专家共识(2020版)[J]. 中华内分泌代谢杂志202036(9):737-750.
[2]
Lenders JWDuh QYEisenhofer G,et al. Pheochromocytoma and paraganglioma: An Endocrine Society Clinical Practice Guideline[J]. J Clin Endocrinol Metab, 2014, 99(6): 1915-1942.
[3]
李赟,李娜,郭宁,等. 妊娠合并嗜铬细胞瘤/副神经节瘤5例临床特征及预后分析[J]. 中国综合临床202238(1):24-29.
[4]
Mohamed Ismail NA, Abd Rahman R, Abd Wahab N, et al. Pheochromocytoma and pregnancy: a difficult and dangerous ordeal[J]. Malays J Med Sci, 2012, 19(1): 65-68.
[5]
Aygun N, Uludag M. Pheochromocytoma and paraganglioma: from clinical findings to diagnosis[J]. Sisli Etfal Hastan Tip Bul, 2020, 54(3):271-280.
[6]
李玉秀,朱惠娟. 协和内分泌疾病诊疗常规[M]. 北京:中国协和医科大学出版社,2021: 332-337.
[7]
Lenders JWM, Langton K, Langenhuijsen JF, et al. Pheochromocytoma and Pregnancy[J]. Endocrinol Metab Clin North Am, 2019, 48(3):605-617.
[8]
孙淑娟.内分泌系统疾病治疗药物处方集[M].北京:人民卫生出版社,2018: 87-93.
[9]
Bancos I, Atkinson E, Eng C, et al. Maternal and fetal outcomes in phaeochromocytoma and pregnancy: a multicentre retrospective cohort study and systematic review of literature[J]. Lancet Diabetes Endocrinol, 20219(1): 13-21.
[10]
Johnson Clark T..约翰·霍普金斯妇产科手册[M].张岩,孙笑,主译. 北京:人民卫生出版社,2020: 204-205.
[11]
Gruber LM, Young WF Jr, Bancos I. Pheochromocytoma and Paraganglioma in Pregnancy: A New Era [J]. Curr Cardiol Rep, 202123(6):60.
[12]
徐丛剑,华克范勤. 实用妇产科学[M].4版. 北京:人民卫生出版社,2017: 229-230.
[13]
Clifton-Bligh RJ. The diagnosis and management of pheochromocytoma and paraganglioma during pregnancy [J]. Rev Endocr Metab Disord, 2023, 24(1):49-56.
[14]
Araujo-Castro M, Nattero Chavez L, Martínez Lorca A, et al. Special situations in pheochromocytomas and paragangliomas: pregnancy, metastatic disease, and cyanotic congenital heart diseases [J]. Clin Exp Med, 202222,3:359-370.
[15]
刘庆香,周伟燕,张传宝.儿茶盼胺及其代谢物的检测现状及标准化期望[J].中华检验医学杂志202043(3):322-327.
[16]
dLenders JW, Duh QY, Eisenhofer G, et al. Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline [J]. J Clin Endocrinol Metab, 201499(6):1915-1942.
[17]
Eisenhofer GPeitzsch MKaden D,et al. Reference intervals for LCMS/MS measurements of plasma free, urinary free and urinary acidhydrolyzed deconjugated normetane phrine, metanephrine and methoxytyramine[J].Clin Chim Acta, 2019490:46-54.
[18]
Misasi G, Pancetti F, Giannini A, et al. Pheochromocytoma diagnosed during pregnancy: a case report [J].Gynecol Endocrinol202036(7): 650-653.
[19]
Langton K, Tufton N, Akker S, et al. Pregnancy and phaeochromocytoma/paraganglioma: clinical clues affecting diagnosis and outcome-a systematic review [J]. BJOG, 2021128(8): 1264-1272.
[20]
Pacak K, Taieb D. Phaeochromocytoma and pregnancy: looking towards better outcomes, less fear, and valuable recommendations [J].Lancet Diabetes Endocrinol, 2021, 9(1):2-3.
[21]
Negro A, Verzicco I, Tedeschi S, et al. Unrecognised pheochromocytoma in pregnancy discovered through metoclopramide-triggered hypertensive emergency [J]. Blood Press, 2021, 30(5):322-326.
[22]
彭光彩,曾淑梅,王夙斐,等. 妊娠期高血压危象合并肾上腺疾病的临床诊治分析[J]. 中华内分泌外科杂志202216(1):119-122.
[1] 李钱梅, 何冠南, 赵婧, 陈曦, 唐玉英, 马丽琼, 梁蓉, 袁桃, 李明星. 早孕期低危妊娠和高危妊娠胎盘微血流成像特征及预后分析[J]. 中华医学超声杂志(电子版), 2024, 21(07): 726-732.
[2] 刘涵, 刘晓菲, 陈翰翰, 陈延君, 张雁. 妊娠期肉芽肿性乳腺炎一例[J]. 中华乳腺病杂志(电子版), 2024, 18(04): 253-254.
[3] 何淳诺, 田志敏, 李焕玺, 吴昊越, 庄凯鹏, 周胜虎, 张浩强. 小儿发育性髋关节发育不良诊治的研究进展[J]. 中华关节外科杂志(电子版), 2024, 18(04): 497-504.
[4] 刘明禹, 马兵. 吸入性损伤早期诊断方法及策略的研究进展[J]. 中华损伤与修复杂志(电子版), 2024, 19(04): 356-359.
[5] 张静, 刘畅, 华成舸. 妊娠期患者口腔诊疗进展[J]. 中华口腔医学研究杂志(电子版), 2024, 18(05): 340-344.
[6] 中国医师协会肝癌专业委员会. 肝细胞癌伴微血管侵犯诊断和治疗中国专家共识(2024版)[J]. 中华普通外科学文献(电子版), 2024, 18(05): 313-324.
[7] 赵林娟, 吕婕, 王文胜, 马德茂, 侯涛. 超声引导下染色剂标记切缘的梭柱型和圆柱型保乳区段切除术的效果研究[J]. 中华普外科手术学杂志(电子版), 2024, 18(06): 634-637.
[8] 屈翔宇, 张懿刚, 李浩令, 邱天, 谈燚. USP24及其共表达肿瘤代谢基因在肝细胞癌中的诊断和预后预测作用[J]. 中华普外科手术学杂志(电子版), 2024, 18(06): 659-662.
[9] 中华人民共和国国家卫生健康委员会医政司. 原发性肝癌诊疗指南(2024年版)[J]. 中华肝脏外科手术学电子杂志, 2024, 13(04): 407-449.
[10] 王天福, 王刚. 自身免疫性胰腺炎诊治现状[J]. 中华肝脏外科手术学电子杂志, 2024, 13(04): 492-497.
[11] 季鹏程, 鄂一民, 陆晨, 喻春钊. 循环外泌体相关生物标志物在结直肠癌诊断中的研究进展[J]. 中华结直肠疾病电子杂志, 2024, 13(04): 265-273.
[12] 胡云鹤, 周玉焯, 付瑞瑛, 于凡, 李爱东. CHS-DRG付费制度下GB1分组住院费用影响因素分析与管理策略探讨[J]. 中华临床医师杂志(电子版), 2024, 18(06): 568-574.
[13] 奚培培, 周加军. 慢性肾脏病患者肌少症机制和诊治的研究进展[J]. 中华临床医师杂志(电子版), 2024, 18(05): 491-495.
[14] 孙双权, 孙玮玮, 王勇, 方道成, 温晖. 肾脏混合性上皮和间质肿瘤一例[J]. 中华临床医师杂志(电子版), 2024, 18(05): 512-515.
[15] 朱旦华, 卢放根. 以腹水为主要特征的Castleman病16例[J]. 中华临床医师杂志(电子版), 2024, 18(05): 462-473.
阅读次数
全文


摘要