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中华产科急救电子杂志 ›› 2024, Vol. 13 ›› Issue (01) : 13 -17. doi: 10.3877/cma.j.issn.2095-3259.2024.01.003

妊娠合并内分泌疾病

妊娠合并甲状旁腺功能减退症的诊治
胡惠英1, 高劲松1,()   
  1. 1. 100730 中国医学科学院 北京协和医学院 北京协和医院妇产科 国家妇产疾病临床医学研究中心
  • 收稿日期:2023-12-08 出版日期:2024-02-18
  • 通信作者: 高劲松
  • 基金资助:
    中央高水平医院临床科研业务费资助(2022-PUMCH-B-075)

Diagnosis and treatment of hypoparathyroidism in pregnancy

Huiying Hu, Jinsong Gao()   

  • Received:2023-12-08 Published:2024-02-18
  • Corresponding author: Jinsong Gao
引用本文:

胡惠英, 高劲松. 妊娠合并甲状旁腺功能减退症的诊治[J]. 中华产科急救电子杂志, 2024, 13(01): 13-17.

Huiying Hu, Jinsong Gao. Diagnosis and treatment of hypoparathyroidism in pregnancy[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2024, 13(01): 13-17.

甲状旁腺功能减退症是妊娠期罕见的合并症,是由于甲状旁腺素产生过少或作用缺陷而导致的一组以低钙、高磷血症和神经肌肉兴奋性增加为临床特点的疾病,临床表现多样,实验室检查为低钙血症、高磷血症、血甲状旁腺素降低或反常的正常。妊娠合并甲状旁腺功能减退症的治疗目标是维持血钙在正常值的低限,治疗药物选择活性维生素D和钙剂。重视患者教育、妊娠期和哺乳期精细化监测和管理、以及及时调整用药方案,是改善母儿预后的保证。

Hypoparathyroidism is a rare complication of pregnancy, which is a group of diseases characterized by hypocalcemia, hyperphosphatemia, and increased neuromuscular excitability due to insufficient production or defective action of parathyroid hormone (PTH). In some aspects, it is similar to the physiological response of pregnancy and is difficult to distinguish. The clinical manifestations are diverse, and the laboratory examination shows hypocalcemia, hyperphosphatemia, decreased blood PTH, or abnormal normal. The therapeutic target for pregnancy complicated with hypothyroidism is to maintain blood calcium at a normal low limit, and active vitamin D and calcium supplements are suggested. Valuing patient education, fine monitoring and management during pregnancy and lactation, and timely adjusting medication plans are the guarantees for improving the prognosis of mothers and infants.

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