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中华产科急救电子杂志 ›› 2024, Vol. 13 ›› Issue (01) : 24 -28. doi: 10.3877/cma.j.issn.2095-3259.2024.01.005

妊娠合并内分泌疾病

围孕期高催乳素血症的诊治与管理
周杨1, 吕淑兰2,()   
  1. 1. 西北工业大学医院妇科,西安 710072
    2. 西安交通大学第一附属医院妇科,西安 710061
  • 收稿日期:2023-07-26 出版日期:2024-02-18
  • 通信作者: 吕淑兰
  • 基金资助:
    陕西省重点研发计划(2022SF-163)

Diagnosis and treatment of hyperprolactinemia during periconception

Yang Zhou, Shulan Lyu()   

  • Received:2023-07-26 Published:2024-02-18
  • Corresponding author: Shulan Lyu
引用本文:

周杨, 吕淑兰. 围孕期高催乳素血症的诊治与管理[J]. 中华产科急救电子杂志, 2024, 13(01): 24-28.

Yang Zhou, Shulan Lyu. Diagnosis and treatment of hyperprolactinemia during periconception[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2024, 13(01): 24-28.

高催乳素血症是临床常见的一种病理生理状态,可由多种生理、病理、药物因素引起,常常导致闭经、溢乳和不孕,多数患者经药物治疗有效并恢复生育能力。高催乳素血症患者的妊娠时机、合并垂体催乳素瘤孕期多巴胺受体激动剂使用原则及孕期监护等均是医患关注重点。本文根据不同原因所致妊娠合并高催乳素血症的诊断及孕前、孕期与产后管理分别进行阐述,以协助临床决策。

Hyperprolactinemia represents a commonly encountered pathological physiological condition in clinical practice. It should be emphasized that hyperprolactinemia is not considered a distinct disease, but rather a physiological state that can be induced by various factors including physiological, pathological, and pharmacological causes. This condition often leads to menstrual irregularities, galactorrhea, and infertility. The majority of patients respond favorably to pharmacological interventions, resulting in the restoration of their reproductive capabilities. However, healthcare providers and patients need to pay particular attention to key aspects such as determining the appropriate time of pregnancy in individuals with hyperprolactinemia, principles for using dopamine agonists (DAs) during pregnancy in those with concurrent pituitary prolactinomas, as well as monitoring during the antenatal period. This article elucidates the diagnosis and management of hyperprolactinemia combined with pregnancy due to different etiologies, addressing preconception care, antenatal management, and postnatal considerations. Its purpose is to facilitate informed clinical decision-making.

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