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中华产科急救电子杂志 ›› 2025, Vol. 14 ›› Issue (04) : 227 -232. doi: 10.3877/cma.j.issn.2095-3259.2025.04.007

妊娠期并发症对女性全生命周期影响

妊娠期糖尿病对母儿的远期影响
向欠欠, 陈练()   
  1. 100191 北京大学第三医院妇产科 国家妇产疾病临床医学研究中心 国家产科专业医疗质量控制中心
  • 收稿日期:2025-06-22 出版日期:2025-11-18
  • 通信作者: 陈练
  • 基金资助:
    国家重点研发计划资助(2021YFC2701500); 国家临床重点专科建设项目(2024)专项资金

Long-term effects of gestational diabetes mellitus on maternal and offspring health

Qianqian Xiang, Lian Chen()   

  • Received:2025-06-22 Published:2025-11-18
  • Corresponding author: Lian Chen
引用本文:

向欠欠, 陈练. 妊娠期糖尿病对母儿的远期影响[J/OL]. 中华产科急救电子杂志, 2025, 14(04): 227-232.

Qianqian Xiang, Lian Chen. Long-term effects of gestational diabetes mellitus on maternal and offspring health[J/OL]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2025, 14(04): 227-232.

妊娠期糖尿病对母儿健康的影响是多维度、跨生命周期的。对于母体而言,妊娠期糖尿病是未来发生2型糖尿病、代谢综合征及心血管疾病的强烈预警信号;对于子代而言,宫内高血糖环境增加其童年至成年期的肥胖、胰岛素抵抗风险,并可能影响其神经、精神发育。本文强调妊娠期糖尿病作为"时间窗"疾病的重要性,重点关注其对母儿的远期影响,呼吁加强孕期精细化管理、建立产后长期随访体系及推行个体化生活方式干预,降低母儿远期疾病风险。

Gestational diabetes mellitus (GDM) exerts multidimensional and life-course impacts on maternal and offspring health. For the mother, GDM serves as a strong predictor for future development of type 2 diabetes, metabolic syndrome, and cardiovascular diseases. For the offspring, the intrauterine hyperglycemic environment increases the risks of obesity and insulin resistance from childhood to adulthood, and may also adversely affect neuropsychiatric development. This review emphasizes GDM as a critical " window-period disease" and prioritizes its long-term consequences for both mothers and children. It calls for implementing precision antenatal management during pregnancy, establishing structured postpartum surveillance systems, and promoting personalized lifestyle interventions. These coordinated approaches are imperative for mitigating long-term disease risks across generations.

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