切换至 "中华医学电子期刊资源库"

中华产科急救电子杂志 ›› 2026, Vol. 15 ›› Issue (03) : 129 -133. doi: 10.3877/cma.j.issn.2095-3259.2026.03.001

述评

子痫前期:警惕母婴健康危害,加强精准防控管理
杨平, 樊尚荣()   
  1. 518036 深圳,北京大学深圳医院妇产科
  • 收稿日期:2026-06-23 出版日期:2026-08-18
  • 通信作者: 樊尚荣
  • 基金资助:
    国家自然科学基金(82171676); 深圳市女性重大疾病早期诊断技术重点实验室(SYSPG20241211173501001)

Preeclampsia: vigilance against maternal and fetal health hazards, strengthening precision prevention and management

Ping Yang, Shangrong Fan()   

  • Received:2026-06-23 Published:2026-08-18
  • Corresponding author: Shangrong Fan
引用本文:

杨平, 樊尚荣. 子痫前期:警惕母婴健康危害,加强精准防控管理[J/OL]. 中华产科急救电子杂志, 2026, 15(03): 129-133.

Ping Yang, Shangrong Fan. Preeclampsia: vigilance against maternal and fetal health hazards, strengthening precision prevention and management[J/OL]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2026, 15(03): 129-133.

图1 子痫前期的发病机制和对母婴健康的远期影响
[1]
Vera-Ponce VJ, Loayza-Castro JA, Ballena-Caicedo J, et al. Global prevalence of preeclampsia, eclampsia, and HELLP syndrome: a systematic review and meta-analysis[J]. Front Reprod Health20257:1706009.
[2]
Oumbarek K, Lkoul A, Mahlaq S, et al. Factors associated with maternal death from severe preeclampsia in the post- pandemic era: a cross-sectional study from Southern Morocco[J]. BMC Pregnancy Childbirth202525(1):1085.
[3]
Zhao Y, Wang Y, Tong F, et al. Epidemiology of maternal hypertensive disorders[J]. Hypertension202582(5):e88-101.
[4]
Cresswell JA, Alexander M, Chong M, et al. Global and regional causes of maternal deaths 2009-20: a WHO systematic analysis[J]. Lancet Glob Health202513(4):e626-634.
[5]
Karumanchi SA. Two decades of advances in preeclampsia research: molecular mechanisms and translational studies[J]. J Clin Invest2024134(15):e184052.
[6]
陈曼曼,王万州,陆取,等. 1990—2021年中国妊娠期高血压疾病发生率及疾病负担趋势基于全球疾病负担数据的分析[J].中华妇产科杂志202560(9):723-731.
[7]
Qiao J, Wang Y, Li X, et al. A Lancet Commission on 70 years of women′s reproductive, maternal, newborn, child, and adolescent health in China[J]. Lancet2021397(10293):2497-2536.
[8]
Li A, Ma Q, Chu Z, et al. Nomogram-based prediction of placental abruption in severe pre-eclampsia based on serum APN, Cys-C, and D-dimer[J]. Front Med (Lausanne)202512:1650160.
[9]
Davidson B, Rayner B, Wearne N, et al. Long-term cardio-renal-metabolic complications following pre-eclampsia[J]. Cardiol Clin202543(3):457-467.
[10]
Voskamp LW, Rousian M, Koerts JJ, et al. Risk factors for chronic hypertension 5-years after a pregnancy complicated by preeclampsia: a systematic review and meta-analysis[J]. J Hypertens202543(6):939-948.
[11]
Keitaanpää N, Tyrmi JS, Toivonen E, et al. Impact of preeclampsia duration on long-term cardiovascular disease risk[J]. Hypertension202683(2):e25054.
[12]
罗漫灵,黄莉萍. 子痫前期对孕产妇心血管系统的远期影响[J/OL]. 中华产科急救电子杂志202514(4): 205-209.
[13]
Auger N, Amar S, Paradis G, et al. Preeclampsia and onset of renal disorders in the long-term period following pregnancy[J]. Am J Nephrol202657(3):352-360.
[14]
李平,张卫社. 子痫前期对孕产妇肾脏功能的远期影响[J/OL]. 中华产科急救电子杂志202514(4): 215-219.
[15]
Martini C, Saeed Z, Simeone P, et al. Preeclampsia: insights into pathophysiological mechanisms and preventive strategies[J]. Am J Prev Cardiol202523:101054.
[16]
Wu P, Green M, Myers JE. Hypertensive disorders of pregnancy[J]. BMJ2023381:e071653.
[17]
Amaral LM, Cunningham MW, Cornelius DC, et al. Preeclampsia: long-term consequences for vascular health[J]. Vasc Health Risk Manag201511:403-415.
[18]
Zhang H, Lin J, Zhao H. Impacts of maternal preeclampsia exposure on offspring neuronal development: recent insights and interventional approaches[J]. Int J Mol Sci202425(20):11062.
[19]
Dachew BA, Mamun A, Maravilla JC, et al. Pre-eclampsia and the risk of autism-spectrum disorder in offspring: meta-analysis[J]. Br J Psychiatry2018212(3):142-147.
[20]
Maher GM, O′Keeffe GW, Dalman C, et al. Association between preeclampsia and autism spectrum disorder: a population-based study[J]. J Child Psychol Psychiatry202061(2):131-139.
[21]
Sun BZ, Moster D, Harmon QE, et al. Association of preeclampsia in term births with neurodevelopmental disorders in offspring[J]. JAMA Psychiatry202077(8):823-829.
[22]
Walker CK, Krakowiak P, Baker A, et al. Preeclampsia, placental insufficiency, and autism spectrum disorder or developmental delay. JAMA Pediatr2015169(2):154-162.
[23]
Zhen Lim TX, Pickering TA, Lee RH, et al. Hypertensive disorders of pregnancy and occurrence of ADHD, ASD, and epilepsy in the child: a meta-analysis[J]. Pregnancy Hypertens202333:22-29.
[24]
Manoharan MM, Montes GC, Acquarone M, et al. Metabolic theory of preeclampsia: implications for maternal cardiovascular health[J]. Am J Physiol Heart Circ Physiol2024327(3):H582-597.
[25]
宋敏敏,熊钰. 子痫前期对子代的影响[J/OL]. 中华产科急救电子杂志202514(4): 220-226.
[26]
Giesen EM, Verlohren S, Blois SM. Multi-omic insights of preeclampsia and cardiovascular health outcomes[J]. Commun Med (Lond)20255(1):446.
[27]
Chen G, Chen Y, Shi Y, et al. A dynamic prediction model for preeclampsia using the sFlt-1/PLGF ratio combined with multiple factors[J]. BMC Pregnancy Childbirth202424(1):443.
[28]
American College of Obstetricians and Gynecologists. Gestational hypertension and preeclampsia: ACOG practice bulletin, Number 222[J]. Obstet Gynecol2020135(6):e237-260.
[29]
中华医学会妇产科学分会妊娠期高血压疾病学组,中华医学会围产医学分会. 子痫前期预测与预防指南(2025)[J]. 中华妇产科杂志202560(5):329-342.
[30]
Snell K, Allotey J, Smuk M, et al. External validation of prognostic models predicting pre-eclampsia: individual participant data meta-analysis[J]. BMC Med202018(1):302.
[31]
Xu Q, Xing L, Zhang T, et al. Development and validation of a preeclampsia prediction model for the first and second trimester pregnancy based on medical history[J]. BMC Pregnancy Childbirth202525(1):616.
[32]
Nadeem M, Javed K, Abid H, et al. A review of dietary and lifestyle management of pre-eclampsia and postpartum eclampsia[J]. Prev Nutr Food Sci202530(1):1-20.
[33]
Poniedziałek-Czajkowska E, Mierzyński R, Leszczyńska-Gorzelak B. Preeclampsia and obesity-the preventive role of exercise[J]. Int J Environ Res Public Health202320(2):1267.
[34]
中华医学会妇产科学分会妊娠期高血压疾病学组.妊娠期高血压疾病诊治指南(2020)[J].中华妇产科杂志202055(4):227-238.
[35]
Countouris M, Mahmoud Z, Cohen JB, et al. Hypertension in pregnancy and postpartum: current standards and opportunities to improve care[J]. Circulation2025151(7):490-507.
[36]
中华医学会心血管病学分会,中华心血管病杂志编辑委员会.妊娠期高血压疾病心血管风险综合管理专家共识[J].中华心血管病杂志202553(3):235-246.
[37]
Jones DW, Ferdinand KC, Taler SJ, et al. 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM guideline for the prevention, detection, evaluation and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines. Hypertension202582(10):e212-316.
[38]
高淑贤,周宇,刘霄,等. 子痫前期对胎儿及子代远期健康的影响:机制、证据与临床转化前景[J]. 现代妇产科进展202635(3):224-228.
No related articles found!
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?