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中华产科急救电子杂志 ›› 2015, Vol. 04 ›› Issue (01) : 44 -47. doi: 10.3877/cma.j.issn.2095-3259.2015.01.010

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RhD母儿血型不合妊娠期管理
殷艳1, 朱启英1,()   
  1. 1. 830054 乌鲁木齐,新疆医科大学第一附属医院妇产科
  • 收稿日期:2014-09-21 出版日期:2015-02-18
  • 通信作者: 朱启英

Management of fetal-maternal hemorrhage of RhD isoimmunization during pregnancy

Yan Yin1, Qiying Zhu1()   

  • Received:2014-09-21 Published:2015-02-18
  • Corresponding author: Qiying Zhu
引用本文:

殷艳, 朱启英. RhD母儿血型不合妊娠期管理[J]. 中华产科急救电子杂志, 2015, 04(01): 44-47.

Yan Yin, Qiying Zhu. Management of fetal-maternal hemorrhage of RhD isoimmunization during pregnancy[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2015, 04(01): 44-47.

RhD母儿血型不合是指来自RhD阴性母体的抗体破坏了RhD阳性胎儿的红细胞,造成胎儿或新生儿溶血,严重者可导致死胎。在广泛应用抗D免疫球蛋白以前,胎儿或新生儿严重溶血发生率很高。规范使用抗D免疫球蛋白预防母儿血型不合和孕期严密监测胎儿状态是降低围产儿发病率和死亡率的关键。

Fetal-maternal hemorrhage of RhD isoimmunization is maternal antibodies of Rh-negative pregnant woman affecting the RhD red cell antigen of Rh-positive fetus, which may result in hemolytic disease of the fetus/newborn, even stillbirth. Prior to the use of anti-D immune globulin, the incidence rate of the fetus/newborn hemolytic disease is high. Implement RhD immune globulin prophylaxis normatively and monitor fetal during pregnancy carefully can led to a significant reduction in the frequency of perinatal mortality and morbidity.

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