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中华产科急救电子杂志 ›› 2015, Vol. 04 ›› Issue (01) : 38 -43. doi: 10.3877/cma.j.issn.2095-3259.2015.01.009

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妊娠合并血友病
陈焱1, 程蔚蔚1,()   
  1. 1. 200030 上海交通大学医学院附属国际和平妇幼保健院产科
  • 收稿日期:2014-09-10 出版日期:2015-02-18
  • 通信作者: 程蔚蔚

Pregnancy complicated with hemophilia

Yan Chen1, Weiwei Cheng1()   

  • Received:2014-09-10 Published:2015-02-18
  • Corresponding author: Weiwei Cheng
引用本文:

陈焱, 程蔚蔚. 妊娠合并血友病[J]. 中华产科急救电子杂志, 2015, 04(01): 38-43.

Yan Chen, Weiwei Cheng. Pregnancy complicated with hemophilia[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2015, 04(01): 38-43.

血友病是一种凝血功能障碍的X染色体隐性遗传性疾病,主要由于凝血因子Ⅷ或Ⅸ缺乏所致。妊娠合并血友病患者在整个孕期和分娩过程中均面临着出血的风险。本文就妊娠合并血友病的产前诊断、孕期管理、分娩方式、治疗及新生儿处理等作一介绍。

Hemophilia is a recessive X-chromosome genetic diseases with coagulation disorders, due to clotting factor Ⅷ or Ⅸ deficiency. Pregnant women with hemophilia could be at risk of bleeding throughout gestation and during delivery. This article introduced the prenatal diagnosis, obstetrical management, delivery mode, therapy and newborn treatment of hemophilia.

表1 血友病A/B的临床分型[2]
表2 血友病A的鉴别诊断实验[2]
图1 APTT纠正试验
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