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中华产科急救电子杂志 ›› 2016, Vol. 05 ›› Issue (03) : 149 -152. doi: 10.3877/cma.j.issn.2095-3259.2016.03.005

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与高龄妊娠相关的几种胎儿疾病
钟世林1, 樊尚荣1,()   
  1. 1. 518036 深圳,北京大学深圳医院妇产科
  • 收稿日期:2016-05-16 出版日期:2016-08-18
  • 通信作者: 樊尚荣

Several fetal abnormalities associated with advanced maternal age

Shilin Zhong1, Shangrong Fan1()   

  • Received:2016-05-16 Published:2016-08-18
  • Corresponding author: Shangrong Fan
引用本文:

钟世林, 樊尚荣. 与高龄妊娠相关的几种胎儿疾病[J]. 中华产科急救电子杂志, 2016, 05(03): 149-152.

Shilin Zhong, Shangrong Fan. Several fetal abnormalities associated with advanced maternal age[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2016, 05(03): 149-152.

高龄妊娠是指孕妇年龄在预产期满35周岁的妊娠,对妊娠和围产儿结局产生重要影响。目前已知高龄妊娠显著增加胎儿染色体畸变的发生,高龄妊娠与胎儿非染色体异常畸形、生长受限等胎儿发育异常相关,加强高龄妊娠相关的胎儿疾病筛查、诊断和处理对降低出生缺陷发生率和围产儿死亡率具有重要意义。

Advanced maternal aged pregnancy (AMAP) is usually defined as pregnancy at the age of 35 years and older, which has been found to be associated with numerous adverse maternal and perinatal outcomes. The AMAP is not only related with the increasing number of fetal chromosome aberration, but also relate with fetal non-chromosomal anomalies and fetal growth retardation. Strengthening the prenatal screening, diagnosis and management of the AMAP associated fetal abnormalities has great significance for reducing the occurrence of birth defects and perinatal mortality.

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