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中华产科急救电子杂志 ›› 2020, Vol. 09 ›› Issue (01) : 25 -30. doi: 10.3877/cma.j.issn.2095-3259.2020.01.007

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双胎自发性早产预测及预防
林琳1, 陈敦金1,()   
  1. 1. 510150 广州医科大学附属第三医院妇产科 广州重症孕产妇救治中心
  • 收稿日期:2018-10-07 出版日期:2020-02-18
  • 通信作者: 陈敦金
  • 基金资助:
    国家重点研发计划(2016YFC1000405); 广东省科技计划项目(粤科规划[2015]110号)

Prediction and prevention of twin spontaneous preterm birth

Lin Lin1, Dunjin Chen1()   

  • Received:2018-10-07 Published:2020-02-18
  • Corresponding author: Dunjin Chen
引用本文:

林琳, 陈敦金. 双胎自发性早产预测及预防[J/OL]. 中华产科急救电子杂志, 2020, 09(01): 25-30.

Lin Lin, Dunjin Chen. Prediction and prevention of twin spontaneous preterm birth[J/OL]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2020, 09(01): 25-30.

随着辅助生殖技术的发展,双胎妊娠的发生率增加,早产的发生率也随之增加。有证据表明,超声检测宫颈长度和胎儿纤维蛋白测试可以预测双胎妊娠的自发性早产,但是到目前为止,没有任何有效的双胎妊娠的自发性早产的干预措施。本文对双胎自发性早产的预测和预防进行阐述。

With the development of assisted reproductive technology, the incidence of twin pregnancies and premature delivery has increased. There has evidence that sonographic cervical length assessment and fetal fibronectin testing can predict spontaneous preterm birth in twin pregnancies, but so far, there has no effective intervention for spontaneous preterm birth in twin pregnancies. This article will describe the prediction and prevention of spontaneous preterm birth in twin pregnancies.

[1]
World Health Organization. Preterm birth[EB/OL]. 2018-2-19/2018-10-2.

URL    
[2]
Khalil MI, Alzahrani MH, Ullah A. The use of cervical length and change in cervical length for prediction of spontaneous preterm birth in asymptomatic twin pregnancies[J]. Eur J Obstet Gynecol Reprod Biol, 2013, 169(2): 193-196.
[3]
Conde-Agudelo A, Romero R, Hassan SS, et al. Transvaginal sonographic cervical length for the prediction of spontaneous preterm birth in twin pregnancies: a systematic review and meta-analysis [J]. Am J Obstet Gynecol, 2010, 203(2): 128.e1-128.e12.
[4]
Fuchs F, Lefevre C, Senat MV, et al. Accuracy of fetal fibronectin for the prediction of preterm birth in symptomatic twin pregnancies: a pilot study [J]. Scientific Reports, 2018, 8(1): 2160.
[5]
刘洋铭,王寒冰,漆洪波. 美国妇产科医师学会早产管理指南2016年补充公告解读[J]. 中国实用妇科与产科杂志,2016, 32(12): 1189-1192.
[6]
Michaluk A, Dionne MD, Gazdovich S, et al. Predicting Preterm Birth in Twin Pregnancy: Was the Previous Birth Preterm A Canadian Experience [J]. J Obstet Gynaecol Can, 2013, 35(9): 793-801.
[7]
Fox NS, Stern E, Gupta S, et al. Preterm Birth or Small for Gestational Age in a Singleton Pregnancyand Risk of Recurrence in a Subsequent Twin Pregnancy [J]. Obstet Gynecol, 2015, 125(4): 870-875.
[8]
Noehr B, Jensen A, Frederiksen K, et al. Loop Electrosurgical Excision of the Cervix and Risk for Spontaneous Preterm Delivery in Twin Pregnancies [J]. Obstet Gynecol, 2009, 114(3): 511-515.
[9]
Pinborg A, Ortoft G, Loft A, et al. Cervical conization doubles the risk of preterm and very preterm birth in assisted reproductive technology twin pregnancies [J]. Human Reproduction, 2014, 30(1): 197-204.
[10]
Rode L, Tabor A. Prevention of preterm delivery in twin pregnancy[J]. Best Pract Res Clin Obstet Gynaecol, 2014, 28(2): 273-283.
[11]
Shennan AH. Prediction and prevention of preterm birth: a quagmire of evidence[J]. Ultrasound Obstet Gynecol, 2018, 51(5): 569-570.
[12]
Conde-Agudelo A, Romero R. Predictive accuracy of changes in transvaginal sonographic cervical length over time for preterm birth: a systematic review and meta-analysis[J]. Am J Obstet Gynecol, 2015, 213(6): 789-801.
[13]
Kindinger LM, Poon LC, Cacciatore S, et al. The effect of gestational age and cervical length measurements in the prediction of spontaneous preterm birth in twin pregnancies: an individual patient level meta-analysis [J]. BJOG, 2016, 123(6): 877-884.
[14]
Asnafi N, Basirat Z, Hajian-Tilaki K, et al. Assessment of cervical length by transvaginal ultrasonography to predict preterm delivery in twin pregnancy[J]. J Matern Fetal Neonatal Med, 2013, 26(14): 1435-1438.
[15]
孙路明,赵扬玉,段涛. 中华医学会"双胎妊娠临床处理指南(第一部分):双胎妊娠孕期监护及处理(2015)"解读[J].中国实用妇科与产科杂志,2016, 32(4): 291-297.
[16]
原鹏波,赵扬玉. 双胎妊娠早产的预防和治疗[J]. 中国实用妇科与产科杂志,2018, 34(2): 154-158.
[17]
Shapiro JL, Kung R, Barrett JF. Cervical length as a predictor of pre-term birth in twin gestations[J]. Twin Res, 2000, 3(4): 213-216.
[18]
Melamed N, Pittini A, Hiersch L, et al. Do serial measurements of cervical length improve the prediction of preterm birth in asymptomatic women with twin gestations [J]. Am J Obstet Gynecol, 2016, 215(5): 616.e1-616.e14.
[19]
Fox NS, Saltzman DH, Klauser CK, et al. Prediction of spontaneous preterm birth in asymptomatic twin pregnancies with the use of combined fetal fibronectin and cervical length[J]. Am J Obstet Gynecol, 2009, 201(3): 313.e1-313.e 5.
[20]
Combs CA, Garite TJ, Maurel K, et al. Fetal Fibronectin versus Cervical Length as Predictors of Preterm Birth in Twin Pregnancy with or without 17-Hydroxyprogesterone Caproate [J]. Am J Perinatol, 2014, 31(12): 1023-1030.
[21]
刘慧翔,张建平. 早产预测新观点解析[J/CD]. 中华产科急救电子杂志,2017, 6(4): 228-233.
[22]
Fichera A, Prefumo F, Zanardini C, et al. Rapid cervical phIGFBP-1 test in asymptomatic twin pregnancies:role in mid-pregnancy prediction of spontaneous preterm delivery[J]. Prenat Diagn, 2014, 34(5): 450-459.
[23]
Tanaka K, Yamada K, Matsushima M, et al. Prediction of spontaneous preterm delivery in asymptomatic twin pregnancies using cervical length and granulocyte elastase [J]. Taiwan J Obstet Gynecol, 2017, 56(2): 188-191.
[24]
Lee SM, Park JS, Norwitz ER, et al. Mid-trimester amniotic fluid pro-inflammatory biomarkers predict the risk of spontaneous preterm delivery in twins:a retrospective cohort study[J]. J Perinatol, 2015, 35(8): 542-526.
[25]
Fuchs F, Senat MV. Multiple gestations and preterm birth [J]. Semin Fetal Neonatal Med, 2016, 21(2):113-120.
[26]
Owen DJ, Wood L, Tomenson B, et al. Social stress predicts preterm birth in twin pregnancies [J]. J Psychosom Obstet Gynaecol, 2017, 38(1): 63-72.
[27]
Csapo A. Progesterone block [J]. Am J Anat, 1956, 98(2): 273-291.
[28]
El-Refaie W, Abdelhafez MS, Badawy A. Vaginal progesterone for prevention of preterm labor in asymptomatic twin pregnancies with sonographic short cervix: a randomized clinical trial of efficacy and safety [J]. Arch Gynecol Obstet, 2016, 293(1): 61-67.
[29]
Schuit E, Stock S, Rode L, et al. Effectiveness of progestogens to improve perinatal outcome in twin pregnancies: an individual participant data meta-analysis [J]. BJOG, 2015, 122(1): 27-37.
[30]
Romero R, Conde-Agudelo A, El-Refaie W, et al. Vaginal progesterone decreases preterm birth and neonatal morbidity and mortality in women with a twin gestation and a short cervix: an updated meta-analysis of individual patient data [J]. Ultrasound Obstet Gynecol, 2017, 49(3): 303-314.
[31]
Houlihan C, Poon LCY, Ciarlo M, et al. Cervical cerclage for preterm birth prevention in twin gestation with short cervix: a retrospective cohort study [J]. Ultrasound in Obstetrics and Gynecology, 2016, 48(6): 752-756.
[32]
Saccone G, Rust O, Althuisius S, et al. Cerclage for short cervix in twin pregnancies: systematic review and meta-analysis of randomized trials using individual patient-level data [J]. Acta Obstet Gynecol Scand, 2015, 94(4): 352-358.
[33]
Berghella V, Roman A. Cerclage in twins: we can do better [J]. Am J Obstet Gynecol, 2014, 211(1): 5-6.
[34]
Nicolaides KH, Syngelaki A, Poon LC, et al. Cervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial [J]. Am J Obstet Gynecol, 2015, 214(1): 1-9.
[35]
Liem S, Schuit E, Hegeman M, et al. Cervical pessaries for prevention of preterm birth in women with a multiple pregnancy (ProTWIN): a multicentre,open-label randomised controlled trial [J]. Lancet, 2013, 382(9901): 1341-1349.
[36]
Fox NS, Gupta S, Lam-Rachlin J, et al. Cervical Pessary and Vaginal Progesterone in Twin Pregnancies With a Short Cervix [J]. Obstet Gynecol, 2016, 127(4): 625-630.
[37]
Berghella V, Dugoff L, Ludmir J. Prevention of preterm birth with pessary in twins(PoPPT):a randomized controlled trial [J]. Ultrasound Obstet Gynecoly, 2017, 49(5): 567-572.
[38]
American College of Obstetricians and Gynecologists; Society for Maternal-Fetal Medicine. Multifetal Gestations: Twin, Triplet, and Higher-Order Multifetal Pregnancies[J]. Obstet Gynecol, 2014, 123(5): 1118-1132.
[39]
Sentilhes L, Sénat MV, Ancel PY, et al. Prevention of spontaneous preterm birth: Guidelines for clinical practice from the French College of Gynaecologists and Obstetricians (CNGOF)[J]. Eur J Obstet Gynecol Reprod Biol, 2017, 210: 217-224.
[40]
Practice Bulletin No. 159: Management of Preterm Labor [J]. Obstet Gynecol, 2016, 127(1): e29-e38.
[41]
Yamasmit W, Chaithongwongwatthana S, Tolosa JE, et al. Prophylactic oral betamimetics for reducing preterm birth in women with a twin pregnancy [J]. Cochrane Database Syst Rev, 2015, (12): CD004733.
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