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中华产科急救电子杂志 ›› 2023, Vol. 12 ›› Issue (01) : 36 -39. doi: 10.3877/cma.j.issn.2095-3259.2023.01.007

病例报告

妊娠合并遗传性抗凝血酶-Ⅲ缺陷症致肠系膜血栓后再次妊娠一例
周艺璇, 代晨阳, 陈汝芳, 黄启涛(), 贺芳   
  1. 佛山市第一人民医院妇产科,佛山 528000
    广州医科大学附属第三医院妇产科 广州重症孕产妇救治中心 广东省产科重大疾病重点实验室,广州 510150
  • 收稿日期:2022-09-13 出版日期:2023-02-18
  • 通信作者: 黄启涛

Repregnancy after mesenteric thrombosis caused by hereditary antithrombin Ⅲ deficiency: a case report

Yixuan Zhou, Chenyang Dai, Rufang Chen   

  • Received:2022-09-13 Published:2023-02-18
引用本文:

周艺璇, 代晨阳, 陈汝芳, 黄启涛, 贺芳. 妊娠合并遗传性抗凝血酶-Ⅲ缺陷症致肠系膜血栓后再次妊娠一例[J]. 中华产科急救电子杂志, 2023, 12(01): 36-39.

Yixuan Zhou, Chenyang Dai, Rufang Chen. Repregnancy after mesenteric thrombosis caused by hereditary antithrombin Ⅲ deficiency: a case report[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2023, 12(01): 36-39.

患者32岁,孕2产0,因"停经34+2周,因肠系膜血栓史要求终止妊娠"于2022年7月19日收入佛山市第一人民医院。患者末次月经2021年11月13日,预产期2022年8月27日。既往史:2019年患者孕17+周时因"肠系膜静脉血栓、胎死宫内"行坏死肠管切除术、取栓术及引产术,术后检测孕妇抗凝血酶-Ⅲ(antithrombin-Ⅲ,AT-Ⅲ)活性为9%,基因检测示:纤溶酶原激活物抑制物-1突变(4G/4G)、F5突变(GG),提示静脉血栓风险高,诊断为遗传性易栓症——AT-Ⅲ缺陷症,予口服华法林(3 mg, 1次/d)抗栓治疗,至本次妊娠早期。

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