Abstract:
Objective To explore the risk factors of preeclampsia with serious complications.
Methods Clinical data of 805 preeclampsia patients and the perinatal infants were retrospective analyzed. Three hundred and twenty-seven cases with serious complications were in the research group, 478 cases without serious complications were in the control group.
Results (1) The incidence of preeclampsia patients with serious complications was 40.6%(327/805 cases). The serious complications of 327 cases were including fetal death (138 cases, 42.2%), HELLP syndrome(71 cases, 21.7%), placental abruption(65 cases, 19.9%), cardiac failure(39 cases, 11.9%), postpartum hemorrhage(39 cases, 11.9%), pneumonedema(36 cases, 11.0%) and so on. (2) The clinical manifestation of the two groups, including onset gestational age, systolic pressure, diastolic pressure, creatinine, alanine aminotransferase, albumin and expecting treatment time had statistical significance, P<0.05. (3) In multivariate logistic regression analysis, the risk factors of preeclampsia serious complications were the gestational age of early onset (OR=0.783, 95%CI: 0.745-0.823), high serum creatinine (OR=1.005, 95%CI: 1.001-1.008), hypoproteinemia (OR=0.961, 95%CI: 0.929-0.994).
Conclusion The risk factors of preeclampsia with serious complications were the gestational age of early onse, kidney function damage and hypoproteinemia.
Key words:
Pre-eclampsia,
Pregnancy complications,
Risk factors
Jingjin Gong, Shiliang Liu, DunJin Chen, Fang He, Wenting Tang. Analysis of risk factors of preeclampsia with serious complications[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2015, 04(04): 225-229.