Clinical analysis of single or twin pregnancy complicated with preeclampsia

doi:10.3877/cma.j.issn.2095-3259.2016.01.010

Abstract

Abstract:

Objective

To explore the clinical features and pregnancy outcomes of single or twin pregnancy complicated with preeclampsia.

Methods

From January 2009 to April 2013, 405 pregnancies complicated with preeclampsia, who were admitted to the Obstetrics department of the Third Affiliated Hospital of Guangzhou Medical University were enrolled in this retrospective study. This study included 43 twin pregnancies in research group and 362 singleton pregnancies in the control group. The clinical features and pregnancy outcomes of the two groups were retrospectively analyzed.

Results

The length of hospital stay in research group and control group were (13.28±11.23) day and (9.48±4.97) day, respectively. There was significant difference in the two groups (t=2.20, P<0.05). In research group, the incidence of cesarean section, premature rupture of membranes, postpartum hemorrhage, heart failure were 97.67%, 13.95%, 11.63% and 11.63%, respectively, which were higher than that in control group (79.83%, 5.25%, 5.25% and 4.14%) with significant difference (P<0.05). In research group, the incidence of newborn infection and jaundice were 25.58% and 48.84%, which were higher than that in control group (15.19% and 32.60%) with significant difference (P<0.05).

Conclusion

Compared to singleton pregnancy complicated with preeclampsia, twin pregnancy complicated with preeclampsia increased the incidence of cesarean section, premature rupture of membranes, postpartum hemorrhage and heart failure, and extended maternal hospital stay.

Key words: Twins, Preeclampsia, Pregnancy outcome

Liyun Kuang, Wenting Tang, Yanmei Zhou, Wen Sun, Jingjin Gong, Xiaomei Li, Xiuying Li, Dunjin Chen. Clinical analysis of single or twin pregnancy complicated with preeclampsia[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2016, 05(01): 40-44.

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Figures/Tables 4

References 18

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分组	例数	年龄(岁，±s)	孕次(次，±s)	产次(次，±s)	初产		发病孕周(周，±s)	分娩孕周(周，±s)	住院时间(d，±s)
分组	例数	年龄(岁，±s)	孕次(次，±s)	产次(次，±s)	例数	百分率(%)	发病孕周(周，±s)	分娩孕周(周，±s)	住院时间(d，±s)
研究组	43	29.72±5.53	2.30±1.20	1.42±0.70	29	67.44	30.49±6.65	33.21±4.81	13.28±11.23
对照组	362	30.49±6.11	2.27±1.47	1.53±0.72	213	58.84	31.21±8.89	34.35±4.02	9.48±4.97
统计值	?	t＝－0.77	t＝0.12	t＝－0.93	χ²＝1.18		t＝－0.52	t＝－1.73	t＝2.20
P值	?	>0.05	>0.05	>0.05	>0.05		>0.05	>0.05	<0.05

分组	例数	年龄(岁，±s)	孕次(次，±s)	产次(次，±s)	初产		发病孕周(周，±s)	分娩孕周(周，±s)	住院时间(d，±s)
分组	例数	年龄(岁，±s)	孕次(次，±s)	产次(次，±s)	例数	百分率(%)	发病孕周(周，±s)	分娩孕周(周，±s)	住院时间(d，±s)
研究组	43	29.72±5.53	2.30±1.20	1.42±0.70	29	67.44	30.49±6.65	33.21±4.81	13.28±11.23
对照组	362	30.49±6.11	2.27±1.47	1.53±0.72	213	58.84	31.21±8.89	34.35±4.02	9.48±4.97
统计值	?	t＝－0.77	t＝0.12	t＝－0.93	χ²＝1.18		t＝－0.52	t＝－1.73	t＝2.20
P值	?	>0.05	>0.05	>0.05	>0.05		>0.05	>0.05	<0.05

组别	例数	入院收缩压(mmHg)	入院舒张压(mmHg)	24 h尿蛋白(g/d)	血肌酐(μmoI/L)
研究组	43	160.07±16.85	102.98±14.63	2.46±2.38	60.12±21.50
对照组	362	167.20±21.68	106.08±16.04	2.64±2.92	60.90±24.49
t值	?	－2.02	－1.21	－0.37	－0.20
P值	?	<0.05	>0.05	>0.05	>0.05
组别	例数	尿素(mmol/L)	尿酸(μmol/L)	丙氨酸转氨酶(U/L)	天冬氨酸转氨酶(U/L)
研究组	43	4.30±1.56	433.16±140.40	44.06±122.46	44.78±86.22
对照组	362	4.69±2.63	420.16±128.57	28.60±57.51	36.68±59.90
t值	?	－0.95	0.62	0.82	0.80
P值	?	>0.05	>0.05	>0.05	>0.05

组别	例数	入院收缩压(mmHg)	入院舒张压(mmHg)	24 h尿蛋白(g/d)	血肌酐(μmoI/L)
研究组	43	160.07±16.85	102.98±14.63	2.46±2.38	60.12±21.50
对照组	362	167.20±21.68	106.08±16.04	2.64±2.92	60.90±24.49
t值	?	－2.02	－1.21	－0.37	－0.20
P值	?	<0.05	>0.05	>0.05	>0.05
组别	例数	尿素(mmol/L)	尿酸(μmol/L)	丙氨酸转氨酶(U/L)	天冬氨酸转氨酶(U/L)
研究组	43	4.30±1.56	433.16±140.40	44.06±122.46	44.78±86.22
对照组	362	4.69±2.63	420.16±128.57	28.60±57.51	36.68±59.90
t值	?	－0.95	0.62	0.82	0.80
P值	?	>0.05	>0.05	>0.05	>0.05

组别	例数	剖宫产		胎盘早剥		胎膜早破		产后出血		心力衰竭
组别	例数	例数	百分率(%)	例数	百分率(%)	例数	百分率(%)	例数	百分率(%)	例数	百分率(%)
研究组	43	42	97.67	3	6.98	6	13.95	5	11.63	5	11.63
对照组	362	289	79.83	21	5.80	19	5.25	19	5.25	15	4.14
χ²值	?	7.04		0.01		5.03		5.03		4.58
P值	?	<0.05		>0.05		<0.05		<0.05		<0.05
组别	例数	低蛋白血症		胸腹水		子痫		HELLP综合征
组别	例数	例数	百分率(%)	例数	百分率(%)	例数	百分率(%)	例数	百分率(%)
研究组	43	3	6.98	2	4.65	1	2.33	2	4.65
对照组	362	7	1.93	7	1.93	23	6.35	31	8.56
χ²值	?	χ²＝2.23		χ²＝0.35		χ²＝0.02		χ²＝0.35
P值	?	>0.05		>0.05		>0.05		>0.05

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