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Chinese Journal of Obstetric Emergency(Electronic Edition) ›› 2020, Vol. 09 ›› Issue (02): 101-105. doi: 10.3877/cma.j.issn.2095-3259.2020.02.009

Special Issue:

• Original Article • Previous Articles     Next Articles

Clinical analysis the pregnant outcomes of women of advanced age with hypertensive disorders complicating pregnancy

Xiaolu Nie1, Shuai Fu1, Yukun Liu1, Jianping Zhang1, Hui Chen1,()   

  1. 1. Department of Obstetrics and gynecology, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou 510120, Guangdong, China
  • Received:2020-03-30 Online:2020-05-18 Published:2020-05-18
  • Contact: Hui Chen
  • About author:
    Corresponding author: Chen Hui, Email:

Abstract:

Objective

To analyze the clinical characteristics of pregnant women of advanced age with hypertensive disorders complicating pregnancy, and to provide the clinical basis for improving the pregnancy outcome.

Methods

A retrospective study was used to collect and analyze the clinical data of 71 cases of hypertensive disorder complicating pregnancy during delivery in Sun Yat-sen Memorial Hospital of Sun Yat-sen University from January 2018 to December 2018. They were divided into two groups according to the age; 24 cases with age ≥35 years old were in the advanced maternal age group and 47 cases with age <35 years old were in the control group. Compare gestational weeks of onset, gestational weeks of admission, gestational weeks of delivery, complications of pregnancy, termination of pregnancy, neonatal weight, the rate of neonatal asphyxia and infant respiratory distress syndrome between the two groups. Student t-test was preformed to normal distributive data and Mann-Whitney U test was used to non-normally distributed variables. Chi-square test was used in count data.

Results

There were significant differences in urea nitrogen (5.49±2.44 mmol/L vs 4.40±1.46 mmol/L, t=-2.342), gestational age at admission (34.86 vs 37.14, t=-2.095), gestational age at delivery(36.07 vs 37.43, t=-2.564), the rate of Cesarean (70.83% vs 42.55%, χ2=5.0920), vaginal delivery (8.33% vs 46.81%, χ2=10.510) and induction of labor (16.67% vs 2.13%, χ2=5.130) between the advanced maternal age group and the control group were statistically significant (P<0.05), while there was no significant difference in the neonatal weight (2680 g vs 2960 g, Z=-1.876), the rate of neonatal asphyxia (8.33% vs 8.51%, χ2=0.001) and infant respiratory distress syndrome (4.17% vs 14.89%, χ2=0.913) among two groups (P>0.05).

Conclusions

The clinical features of women of advanced age with hypertensive disorders complicating pregnancy were earlier onset, more serious renal function damage, earlier pregnancy termination, higher rate of premature delivery and Cesarean, lower rate of vaginal delivery. More closely monitoring should be given to the women of advanced age.

Key words: Advanced maternal age, Hypertensive disorders complicating, Pregnant outcomes

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