Diagnosis, management and counseling of cytomegalovirus infection during pregnancy

doi:10.3877/cma.j.issn.2095-3259.2020.04.003

Abstract

Abstract:

This review article provides the information on the incidence of intrauterine transmission in various types of maternally active cytomegalovirus (CMV) infection, the differentiation of active CMV in pregnant women, and the diagnosis of fetal CMV infection. This document clearly states that the prenatal counseling should be based on the combination of the status of fetal CMV infection and the results of fetal imaging. It is emphasized that the pregnancy should not be terminated only based on the maternal positive for CMV IgM and IgG. Detection of CMV DNA in breastmilk is not required and breastmilk beefing should be encouraged.

Key words: Cytomegalovirus, Active infection, Intrauterine transmission, Diagnosis, Management, Counseling

Jing Feng, Yihua Zhou. Diagnosis, management and counseling of cytomegalovirus infection during pregnancy[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2020, 09(04): 199-203.

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References 22

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IgM	IgG	临床意义
-	-	未感染，易感人群，存在原发感染风险
-	＋	潜伏感染，通常无需进一步检查
＋	＋	活动性感染：原发感染或非原发感染^a
＋	-	假阳性或感染初期，1～2周后复查
1～2周后复查结果
＋	-	假阳性，排除感染
＋	＋	真阳性，原发感染
-	＋	真阳性，原发感染

IgM	IgG	临床意义
-	-	未感染，易感人群，存在原发感染风险
-	＋	潜伏感染，通常无需进一步检查
＋	＋	活动性感染：原发感染或非原发感染^a
＋	-	假阳性或感染初期，1～2周后复查
1～2周后复查结果
＋	-	假阳性，排除感染
＋	＋	真阳性，原发感染
-	＋	真阳性，原发感染

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