Long-term effects of gestational diabetes mellitus on maternal and offspring health

doi:10.3877/cma.j.issn.2095-3259.2025.04.007

Abstract

Abstract:

Gestational diabetes mellitus (GDM) exerts multidimensional and life-course impacts on maternal and offspring health. For the mother, GDM serves as a strong predictor for future development of type 2 diabetes, metabolic syndrome, and cardiovascular diseases. For the offspring, the intrauterine hyperglycemic environment increases the risks of obesity and insulin resistance from childhood to adulthood, and may also adversely affect neuropsychiatric development. This review emphasizes GDM as a critical " window-period disease" and prioritizes its long-term consequences for both mothers and children. It calls for implementing precision antenatal management during pregnancy, establishing structured postpartum surveillance systems, and promoting personalized lifestyle interventions. These coordinated approaches are imperative for mitigating long-term disease risks across generations.

Key words: Diabetes, gestational, long-term consequences, Prevention

Qianqian Xiang, Lian Chen. Long-term effects of gestational diabetes mellitus on maternal and offspring health[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2025, 14(04): 227-232.

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