A comparative study of two placental pathological sampling methods on detection rate of uteroplacental vessels

doi:10.3877/cma.j.issn.2095-3259.2026.03.005

Abstract

Abstract:

Objective

To investigate the influence of different placental pathological sampling methods on the detection rate of uteroplacental vessels and the accuracy of placental pathological diagnosis.

Methods

(1) Based on the ultrasonic blood flow signals of different placental locations, a new placental sampling method was proposed (new method group) and compared with the conventional placental sampling method recommended by the Amsterdam Consensus (conventional method group), in terms of the detection rate of uteroplacental vessels and the accuracy of placental pathological diagnosis. (2) There were 176 patients in the new method group, 57 of whom were clinically diagnosed as hypertensive disorders of pregnancy (HDP); 129 patients in the conventional method group, 43 of whom were HDP. The detection rate of uteroplacental vessels and the diagnostic rate of placental maternal vascular malperfusion (MVM) were compared between the two groups.

Results

(1) In the detection rate of uteroplacental vessels, comparison of HDP placentas showed that the new method group was significantly higher than the conventional method group (70.2% vs 39.5%, Z=-3.057, P=0.002). (2) Comparison of different placental positions showed that the detection rate of blood vessels located at the placental margin was the highest (54.4%, U=13.841, P=0.003). (3) The diagnostic rate of MVM of HDP in the new method group was higher than that in the conventional method group (59.6% vs 32.6%, Z=-2.671, P=0.008).

Conclusions

The new placental sampling method can obtain more uteroplacental vessels for histopathological evaluation and demonstrate more comprehensive lesion information, which improves the accuracy of placental pathological diagnosis and standardizes placental sampling criteria.

Key words: Placenta, Sampling method, Uteroplacental vessels, Pathology

Zhongfeng Yang, Ping Qin, Shaoyan Liu, Li Zhao, Bin Yu, Xuexian Tan, Qingping Jiang. A comparative study of two placental pathological sampling methods on detection rate of uteroplacental vessels[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2026, 15(03): 151-157.

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References 24

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组别	例数	0根	1~3根	≥4根
常规方法组	129	60(46.5)	65(50.4)	4(3.1)
新方法组	176	69(39.2)	92(52.3)	15(8.5)
Z值		－1.678
P值		0.093

组别	例数	0根	1~3根	≥4根
常规方法组	129	60(46.5)	65(50.4)	4(3.1)
新方法组	176	69(39.2)	92(52.3)	15(8.5)
Z值		－1.678
P值		0.093

组别	例数	0根	1~3根	≥4根
常规方法组	43	26(60.5)	15(34.9)	2(4.7)
新方法组	57	17(29.8)	33(57.9)	7(12.3)
Z值		－3.057
P值		0.002

组别	例数	0根	1~3根	≥4根
常规方法组	43	26(60.5)	15(34.9)	2(4.7)
新方法组	57	17(29.8)	33(57.9)	7(12.3)
Z值		－3.057
P值		0.002

取材位置	0根	1－3根	≥4根
胎盘边缘	26(45.6)	27(47.4)	4(7.0)
脐带附着处	43(75.4)	13(22.8)	1(1.8)
胎盘中央	41(71.9)	15(26.3)	1(1.8)
胎盘最厚处	36(63.2)	20(35.1)	1(1.8)
U值	13.841
P值	0.003

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