The impact of intraspinal analgesia on vaginal delivery in pregnant women with Group B hemolytic streptococcus

doi:10.3877/cma.j.issn.2095-3259.2024.02.010

Abstract

Abstract:

Objective

To investigate the impact of intravertebral analgesia on the outcome of vaginal delivery in pregnant women with Group B streptococcus (GBS).

Methods

A total of 212 pregnant women with GBS were retrospectively selected from January 2022 to December 2022 in the Affiliated Suzhou Hospital of Nanjing Medical University, 106 pregnant women with intraspinal analgesia were selected as the study group and 106 pregnant women without intraspinal analgesia were selected as the control group. The perinatal outcomes of pregnant women and newborns in the two groups were compared.

Results

There were no significant differences in age, BMI, gravida, para and gestational weeks between the two groups (P>0.05). The postpartum blood loss [(284.34±67.13)ml vs (262.78±80.45)ml], the first stage of labor [(453.62±149.03)min vs (411.22±136.25)min], the second stage of labor [(46.11±19.33)min vs (40.59±17.22)min] and intrapartum fever [21(19.81%) vs 6(5.66%)] in the study group were higher than those in the control group, the differences were statistically significant (P<0.05). There were no significant differences in the third stage of labor, lateral perineal incision, vaginal midwifery, cesarean section and postpartum hemorrhage between the two groups (P>0.05). There were no significant differences in neonatal weight, Apgar score (1 min, 5 min), cord blood pH, BE, neonatal asphyxia and NICU admission between the two groups (P>0.05).

Conclusions

Intravertebral analgesia in pregnant women with GBS in labor can significantly relieve pain, and the first and second stages of labor may be prolonged. However, it does not affect the perinatal outcome of mother and newborns, and is a safe and effective way of labor analgesia.

Key words: Analgesia, obstetrical, Streptococcus agalactiae, Vagina, Labor, obstetric, Pregnancy outcome

Xiaoyan Wang, Liping Zhu, Shunyu Hou, Yongfei Yue. The impact of intraspinal analgesia on vaginal delivery in pregnant women with Group B hemolytic streptococcus[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2024, 13(02): 112-116.

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References 23

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组别	例数	年龄(岁，±s)	体质指数(kg/m²，±s)	孕次[次(P₂₅，P₇₅)]	产次[次(P₂₅，P₇₅)]	孕周(周，±s)	产后出血量(ml，±s)
研究组	106	29.98±3.36	26.33±3.05	1(1，2)	1(1，2)	39.24±0.99	284.34±67.13
对照组	106	29.96±3.59	27.10±4.23	1(1，2)	1(1，2)	39.33±1.13	262.78±80.45
统计值		t＝0.040	t＝1.510	Z＝1.055	Z＝1.380	t＝0.562	t＝2.118
P值		0.968	0.127	0.291	0.168	0.574	0.035

组别	例数	年龄(岁，±s)	体质指数(kg/m²，±s)	孕次[次(P₂₅，P₇₅)]	产次[次(P₂₅，P₇₅)]	孕周(周，±s)	产后出血量(ml，±s)
研究组	106	29.98±3.36	26.33±3.05	1(1，2)	1(1，2)	39.24±0.99	284.34±67.13
对照组	106	29.96±3.59	27.10±4.23	1(1，2)	1(1，2)	39.33±1.13	262.78±80.45
统计值		t＝0.040	t＝1.510	Z＝1.055	Z＝1.380	t＝0.562	t＝2.118
P值		0.968	0.127	0.291	0.168	0.574	0.035

组别	例数	产程时间(min, ±s)			分娩结局[例(%)]
组别	例数	第一产程	第二产程	第三产程	产时发热	会阴侧切	阴道助产	中转剖宫产	产后出血
研究组	106	453.62±149.03	46.11±19.33	19.15±7.27	21(19.81)	18(18.37)	7(7.14)	8(7.55)	7(6.60)
对照组	106	411.22±136.25	40.59±17.22	18.03±7.38	6(5.66)	15(14.85)	4(3.96)	5(4.72)	5(4.72)
统计值		t＝2.162	t＝2.193	t＝1.115	χ²＝9.550	χ²＝0.444	χ²＝0.965	χ²＝0.738	χ²＝0.353
P值		0.032	0.029	0.266	0.002	0.505	0.326	0.390	0.552

组别	例数	产程时间(min, ±s)			分娩结局[例(%)]
组别	例数	第一产程	第二产程	第三产程	产时发热	会阴侧切	阴道助产	中转剖宫产	产后出血
研究组	106	453.62±149.03	46.11±19.33	19.15±7.27	21(19.81)	18(18.37)	7(7.14)	8(7.55)	7(6.60)
对照组	106	411.22±136.25	40.59±17.22	18.03±7.38	6(5.66)	15(14.85)	4(3.96)	5(4.72)	5(4.72)
统计值		t＝2.162	t＝2.193	t＝1.115	χ²＝9.550	χ²＝0.444	χ²＝0.965	χ²＝0.738	χ²＝0.353
P值		0.032	0.029	0.266	0.002	0.505	0.326	0.390	0.552

组别	例数	出生体重(g，±s)	Apgar评分[分(P₂₅，P₇₅)]		脐血pH(±s)	脐血剩余碱(mmol/L，±s)	新生儿窒息[例(%)]	入住NICU[例(%)]
组别	例数	出生体重(g，±s)	1 min	5 min	脐血pH(±s)	脐血剩余碱(mmol/L，±s)	新生儿窒息[例(%)]	入住NICU[例(%)]
研究组	106	3325.00±376.21	10(10，10)	10(10，10)	7.24±0.25	9.29±4.66	4(3.77)	2(1.89)
对照组	106	3248.11±410.22	10(10，10)	10(10，10)	7.26±0.30	8.61±4.20	2(1.89)	1(0.94)
统计值		t＝1.422	Z＝0.308	Z＝0.469	t＝0.603	t＝1.112	χ²＝0.686	χ²＝0.338
P值		0.156	0.758	0.639	0.547	0.267	0.407	0.561

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