Postpartum hemorrhage (PPH) is the primary cause of maternal mortality in China. Exploring effective treatments for PPH is of great significance in reducing maternal mortality. Transcatheter Arterial Embolization (TAE) has become one of the crucial interventions for treating PPH. However, this technique requires a high level of operational experience from practitioners and comprehensive capabilities from medical institutions. Standardized referral processes and collaborative mechanisms among regional medical centers are essential for improving the prognosis of PPH. Therefore, it is vital for hospitals at all levels to master the indications, optimal surgical timing for TAE, and methods to prevent its complications. This article delves into the indications, application timing, and prevention of complications associated with TAE in cases of severe PPH.