围产窒息是导致新生儿死亡和残疾的主要原因，胎儿或新生儿因缺氧引起酸中毒，并进一步导致多器官损伤，严重者发生脑瘫或死亡。新生儿复苏方法的进展包括：(1)开始时应用21%氧气复苏足月新生儿，应用空氧混合仪根据血氧饱和度调整给氧浓度。(2)应用T组合复苏器或需要时应用有呼气末正压(PEEP)的自动充气复苏囊正压给氧。(3)有条件者应用三导联心电图监测心率和应用脉氧仪监测心率和氧饱和度。(4)有效正压通气后心率<60次/min，应立即予气管插管，在正压通气同时须进行胸外按压，采用双手环抱双拇指法胸外按压。(5)正压通气和胸外按压后，心率持续<60次/min应用肾上腺素可经脐静脉或气管内途径给药。(6)应用MRSOPA策略改善通气。

Birth asphyxia is the main cause of neonatal disability and deaths. Fetal or neonatal acidosis can be caused by hypoxia, and further lead to multiple organ damage, even cerebral palsy or death. The progress of neonatal resuscitation methods includes: (1) Recommend 21% oxygen for initial resuscitation of term infants and use a blender to titrate inspired oxygen based on pulse oximeter values. (2) Use the positive end expiratory pressure (PEEP) preferably with a T-piece resuscitator. (3) If possible, monitor the heart rate by 3 channel digital electrocardiogram and monitor the oxygen saturation by pulse oximeter. (4) If the heart rate is less than 60 beats per min after effective positive pressure ventilation, tracheal intubation should be performed immediately. During positive pressure ventilation, chest compression with two-thumb technique should be carried out at the same time. (5) After positive pressure ventilation and chest compression, the heart rate last less than 60 beats per min, epinephrine should be administered via umbilical vein or endotracheal route. (6) Strategy of MRSOPA is used to improve ventilation.