分析不同亚型子痫前期患者的母儿结局。

回顾性分析2009年1月1日至2019年12月31日在广州医科大学附属第三医院分娩的2960例单胎子痫前期患者早产组与足月产组、早发型组与晚发型组的临床资料及母儿结局。

(1)母亲结局：①早产组与足月产组剖宫产率分别为(80.85% vs 61.67%, χ²＝1.327)、入住重症监护病房率(11.84% vs 2.25%, χ²＝86.844)，P值均<0.05；②早发型与晚发型剖宫产率分别为(77.61% vs 70.30%, χ²＝1.327，P<0.05)、入住重症监护病房率(13.00% vs 4.55%, χ²＝69.158，P<0.05)。(2)新生儿结局：①早产组与足月产组在新生儿出生平均体重[(1472.19±673.50)g与(3067.49±523.92)g，Z＝-42.4]，活产比例(81.35% vs 99.31%, χ²＝2.204)，新生儿窒息率(6.39% vs 0.79%, χ²＝53.51)P均<0.05。②早发型组与晚发型组新生儿出生体重[(1169.53±482.39)g vs(2765.37±683.22)g，Z＝-43.895]，活产比例(74.64% vs 98.31%, χ²＝3.926)，新生儿窒息率(8.71% vs 1.31%, χ²＝86.82)，差异均有统计学意义(P<0.05)。

子痫前期患者早产组与足月产组相比，早产组母体及新生儿结局均较差。早发型与晚发型子痫前期相比，早发型母儿结局均较差。

To analyze the maternal and neonatal outcomes of patients with different subtype of preeclampsia.

A retrospective analysis was performed on the clinical data and maternal and infant outcomes of 2960 singleton patients with or without early-onset/late onset preeclampsia, who delivered from January 1, 2009 to December 31, 2019 in the Third Affiliated Hospital of Guangzhou Medical University.

(1) Maternal outcomes: ① Compared with the preterm preeclampsia group and term preeclalmpsia group, the rates of cesarean section were 80.85% and 61.67%, respectively ( χ²=1.327), the rates of admission to the intensive care unit was respectively 11.84% and 2.25% ( χ²=86.844); ② The rates of early-onset preeclampsia and late-onset preeclampsia cesarean section was 77.61% and 70.30%, respectively ( χ²=1.327, P<0.05). Admission rate of intensive care unit was 13.00% and 4.55%, respiectively in early-onset group and late-onset group ( χ²=69.158, P<0.05). (2) Neonatal outcomes: ① The mean birth weight of newborns was respectively (1472.19±673.50)g and (3067.49±523.92)g (Z=-42.4), the proportion of live births was respectively 81.35% and 99.31% comparing in early-onset group and late-onset group ( χ²=2.204). The rate of neonatal asphyxia was 6.39% and 0.79%, respectively in two groups ( χ²=53.51, all P<0.05). ② Neonatal birth weight in early-onset group and late-onset group was respectively (1169.53±482.39)g and (2765.37±683.22)g (Z=-43.895), live birth ratio was 74.64% and 98.31% ( χ²=3.926), the rate of neonatal asphyxia was 8.71% and 1.31%, comparing in the two groups ( χ²=86.82). The difference was statistically significant (P<0.05).

Compared with preterm preeclampsia and term preeclampsia, the maternal and neonatal outcomes were worse in preterm preeclampsia. Compared with the late-onset group, maternal and child outcomes were worse in the early-onset group.