Abstract:
Objective To explore the clinical manifestation, laboratory tests, diagnosis, treatment and prognosis of postpartum hemolytic uremic syndrome (PPHUS).
Methods Six cases of PPHUS diagnosed in the Affiliated Suzhou Hospital of Nanjing Medical University from January 2008 to December 2011 were retrospectively analyzed.
Results After cesarean section 24 hours, 6 patients all had anuria, acute renal failure, microangiopathic hemolytic anemia and progressive thrombocytopenia. After a series of treatments, including blood purification, plasma exchange, hemodialysis, infusions of fresh frozen plasma, adrenal cortex hormones, anti-infection, anti-hypertensive and so on, 1 case recovered and 5 cases improved and discharged. In these 5 cases, 4 cases got renal function recovery during 3-6 months of follow-up and 1 case left hospital without cure, whose renal function was still abnormal after 6 months of follow-up.
Conclusions PPHUS is rare and an emergency severe disease. Early diagnosis and correct treatment are helpful to improve the outcomes of PPHUS.
Key words:
Postpartum hemolytic uremic syndrome,
Early diagnosis,
Early treatment,
Hemofiltration,
Plasmapheresis
Li YAN, Yun WANG. Postpartum hemolytic uremic syndrome: six cases reports[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2012, 01(02): 117-121.