Progress in etiological analysis, diagnosis and treatment of hydrops fetails

doi:10.3877/cma.j.issn.2095-3259.2018.01.006

Abstract

Abstract:

Hydrops fetails is a pathologic condition in the fetus characterized by extensive subcutaneous tissue edema and an accumulation of fluid in fetal compartments. The etiology and pathogenesis of hydrops fetails is complex; it is divided into immune hydrops and non-immune hydrops according to the etiology. This article discusses the advances in pathogenesis, etiology, diagnosis and treatment of hydrops fetalis.

Key words: Hydrops fetalis, Etiology, Ultrasonography, Prenatal diagnosis

Fang Yang, Cailing Xu. Progress in etiological analysis, diagnosis and treatment of hydrops fetails[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2018, 07(01): 24-29.

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References 33

[1]	Yeom W, Paik ES, An JJ, et al. Clinical characteristics and perinatal outcome of fetal hydrops [J]. Obstet Gynecol Sci, 2015, 58(2): 90-97.
[2]	Lin SM, Wang CH, Zhu XY, et al. Clinical study on 156 cases with hydrops fetalis [J]. Zhonghua Fu Chan Ke Za Zhi, 2011, 46(12): 905-910.
[3]	Bellini C, Hennekam RC, Fulcheri E, et al. Etiology of nonimmune hydrops fetalis: a systematic review [J]. Am J Med Genet A, 2009, 149(5): 844-851.
[4]	An X, Wang J, Zhuang X, et al. Clinical features of neonates with hydrops fetalis[J]. Am J Perinatol, 2015, 32(13): 1231-1239.
[5]	Liumbruno GM, D′Alessandro A, Rea F, et al. The role of antenatal immunoprophylaxis in the prevention of maternal-foetal anti-Rh(D) alloimmunisation [J]. Blood Transfus, 2010, 8(1): 8-16.
[6]	Nassr AA, Ness A, Hosseinzadeh P, et al. Outcome and Treatment of Antenatally Diagnosed Nonimmune Hydrops Fetalis [J]. Fetal Diagn Ther, 2018, 43(2): 123-128.
[7]	Bellini C, Donarini G, Paladini D, et al. Etiology of non-immune hydrops fetalis: An update [J]. Am J Med Genet A, 2015, 167(5): 1082-1088.
[8]	Yuan S. Cardiac Etiologies of hydrops fetalis [J]. Z Geburtshilfe Neonatol, 2017, 221(2): 67-72.
[9]	Sohan K, Carroll SG, De La Fuente S, et al. Analysis of outcome in hydrops fetalis in relation to gestational age at diagnosis, cause and treatment [J]. Acta Obstet Gynecol Scand, 2001, 80(8): 726-730.
[10]	Arcasoy MO, Gallagher PG. Hematologic disorders and nonimmune hydrops fetalis [J]. Semin Perinatol, 1995, 19(6): 502-515.
[11]	Fay RA. Feto-maternal haemorrhage as a cause of fetal morbidity and mortality [J]. Br J Obstet Gynaecol, 1983, 90(5): 443-446.
[12]	Jatavan P, Chattipakorn N, Tongsong T. Fetal hemoglobin Bart′s hydrops fetalis: pathophysiology, prenatal diagnosis and possibility of intrauterine treatment [J]. J Matern Fetal Neonatal Med, 2018, 31(7): 946-957.
[13]	Liao C, Wei J, Li Q, et al. Nonimmune hydrops fetalis diagnosed during the second half of pregnancy in Southern China[J]. Fetal Diagn Ther, 2007, 22(4): 302-305.
[14]	Liao C, Mo QH, Li J, et al. Carrier screening for alpha- and beta-thalassemia in pregnancy: the results of an 11-year prospective program in Guangzhou Maternal and Neonatal hospital [J]. Prenat Diagn, 2005, 25(2): 163-171.
[15]	Martin-Almedina S, Martinez-Corral I, Holdhus R, et al. EPHB4 kinase-inactivating mutations cause autosomal dominant lymphatic-related hydrops fetalis [J]. J Clin Invest, 2016, 126(8): 3080-3088.
[16]	Brock WW, Bradshaw WT. Congenital Chylothorax: A Unique Presentation of Nonimmune Hydrops Fetalis in a Preterm Infant [J]. Adv Neonatal Care, 2016, 16(2): 114-123.
[17]	Moreno CA, Kanazawa T, Barini R, et al. Non-immune hydrops fetalis: A prospective study of 53 cases [J]. Am J Med Genet A, 2013, 161(12): 3078-3086.
[18]	Gimovsky AC, Luzi P, Berghella V. Lysosomal storage disease as an etiology of nonimmune hydrops [J]. Am J Obstet Gynecol, 2015, 212(3): 281-290.
[19]	Tolfvenstam T, Broliden K. Parvovirus B19 infection [J]. Semin Fetal Neonatal Med, 2009, 14(4): 218-221.
[20]	Weitz J, Das S. Acute non-immune hydrops fetalis caused by intrauterine echovirus infection [J]. BMJ Case Rep, 2010, 2010. pii: bcr0320102787
[21]	Loh KC, Jelin E, Hirose S, et al. Microcystic congenital pulmonary airway malformation with hydrops fetalis: steroids vs open fetal resection [J]. J Pediatr Surg, 2012, 47(1): 36-39.
[22]	Lai CW, Shek NW. Fetal meconium peritonitis and maternal liver disease [J]. Obstet Gynecol, 2016, 127(4): 740-743.
[23]	Norton ME, Chauhan SP, Dashe JS. Society for maternal-fetal medicine (SMFM) clinical guideline #7: nonimmune hydrops fetalis [J]. Am J Obstet Gynecol, 2015, 212(2): 127-139.
[24]	Hartge D R, Weichert J, Gembicki M, et al. Confirmation of etiology in fetal hydrops by sonographic evaluation of fluid allocation patterns [J]. Eur J Obstet Gynecol Reprod Biol, 2015, 195: 128-132.
[25]	Mari G, Deter RL, Carpenter RL, et al. Noninvasive diagnosis by Doppler ultrasonography of fetal anemia due to maternal red-cell alloimmunization. Collaborative Group for Doppler Assessment of the Blood Velocity in Anemic Fetuses [J]. N Engl J Med, 2000, 342(1): 9-14.
[26]	贺欣然，孙瑜. 2015美国母胎医学会——非免疫性胎儿水肿临床指南解读 [J]. 中国医刊，2015, 22(8)：21-25.
[27]	Desilets V, Audibert F. Investigation and management of non-immune fetal hydrops [J]. J Obstet Gynaecol Can, 2013, 35(10): 923-938.
[28]	Eiland S, Cvetanovska E, Bjerre AH, et al. Mirror syndrome is a rare complication in pregnancy, characterized by oedema and hydrops fetalis [J]. Ugeskr Laeger, 2017, 179(15). pii: V12160871.
[29]	Thorsten B, Martin B, Ilka F, et al. Mirror syndrome: a systematic review of fetal associated conditions, maternal presentation and perinatal outcome [J]. Fetal Diagnosis and Therapy, 2010, 27(4): 191-203.
[30]	Hamza A, Herr D, Solomayer E, et al. Polyhydramnios: Causes, diagnosis and therapy [J]. Geburtsh Frauenheilk, 2013, 73(12): 1241-1246.
[31]	Strizek B, Berg C, Gottschalk I, et al. High-dose flecainide is the most effective treatment of fetal supraventricular tachycardia [J]. Heart Rhythm, 2016, 13(6): 1283-1288.
[32]	Roberts D, Neilson JP, Kilby MD, et al. Interventions for the treatment of twin-twin transfusion syndrome [J]. Cochrane Database Syst Rev, 2014, (1): CD002073.
[33]	Santo S, Mansour S, Thilaganathan B, et al. Prenatal diagnosis of non-immune hydrops fetalis: what do we tell the parents？[J]. Prenat Diagn, 2011, 31(2): 186-195.

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