To analyze clinical characteristics of the patients with severe preeclampsia and eclampsia under different antenatal examination situations.

From October 2012 to April 2015, 307 singleton pregnant patients with severe preeclampsia and eclampsia admitted to Qingyuan City People′s Hospitalwere were enrolled in this retrospective study. According to antenatal examination, patients were divided into 3 groups. Thirty-six cases were in never examination group, 146 cases were in irregular examination group, 125 cases were in regular examination group. According to examination hospital, regular antenatal examination patients were divided into 3 groups. Seventeen cases were in grape-one hospitals examination group, 37 cases were in grape-two hospitals examination group, 71 cases were in grape-three hospitals examination group. Clinical general information and pregnancy outcomes of different groups were compared.

(1)Maternal complications: The incidences of maternal complications in never examination group, irregular examination group and regular examination group were 33.3%, 17.1% and 8.8%, respectively. There was significant difference between never examination group and regular examination group (χ²=-0.292, P<0.017). The incidences of ICU admission in the 3 groups were 16.7%, 4.6% and 1.6%, respectively. Compare with never examination, irregular examination group and regular examination group were significant difference (χ²=-0.202 and χ²=-0.289, P<0.017)(2)Perinatal fetus outcomes: The adverse outcomes of perinatal fetuses were fetal distress, mild asphexia, fetal growth restriction, NICU admission, hypoglycemia and neonatal death. There were significant differences between never examination group and regular examination group. (3) The incidences of very low birth weight infant in grape-two and grape-three hospitals were 16.2% and 1.4%, and there was significant difference (χ²=-0.285, P<0.017). The incidence of NICU admission in grape-two and grape-three hospitals were 40.5% and 15.5%, and there was also significant difference (χ²=-0.278, P<0.017).

Under regular antenatal examination, even severe preeclampsia and eclampsia patients in the different grapes hospitals can detect early clinical abnormalities and have timely treatment to improve the pregnancy outcomes.