To explore the clinical characteristics of preeclampsia with obstructive sleep apnea hypopnea syndrome(OSAHS)and the short-term outcomes of mother and newborn.

68 pregnant women with preeclampsia, who were admitted to Dongguan people′s hospital from June 2018 to June 2019, were selected. The patients were divided into two groups. 32 patients in OSAHS group, were diagnosed as OSAHS by polysomnography (PSG). 36 patients did not meet the diagnostic criteria, who were set as Non-OSAHS group. Clinical data of two groups were collected for analysis.

There were no significant difference in age, incidence of severe eclampsia and gestational age between two groups (P>0.05). The number of pregnant women with irregular prenatal examination in OSAHS group was higher than in Non-OSAHS group (P<0.05). The ESS score (9.25±3.51) and AHI [(10.56±3.40) /h] were higher in OSAHS group than that in Non-OSAHS group (P<0.01). The lowest nighttime SpO₂ [(85.22±3.40) %] was lower in OSAHS group than that in Non-OSAHS group (P<0.01). The pre-pregnancy BMI [(23.76±3.38) kg/m²], weight gain in early pregnancy [(1.62±1.03) kg] and neck circumference [(36.72±3.07) cm] in the OSAHS group were higher than those [(22.02±2.57)kg/m²、(0.87±0.93)kg、(35.17±2.27)cm] in the non-OSAHS group (P<0.01). The incidence of preterm delivery in OSAHS group was higher than in Non-OSAHS group (P<0.05). Neonatal asphyxia rate, Apgar score and the rate of newborn transferring to NICU in OSAHS group were significantly higher than in Non-OSAHS group (P<0.05). However, there were no significant difference in birth weight and tracheal intubation rate in two groups.

Pregnant women with snore should be paid more attention. High pre-pregnancy BMI, excessive weight gain in early pregnancy and excessive neck circumference are the risk factors for preeclampsia patients to have OSAHS. Timely diagnosis and effectively intervention of OSAHS may promote maternal and infant health.