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中华产科急救电子杂志 ›› 2026, Vol. 15 ›› Issue (03) : 134 -140. doi: 10.3877/cma.j.issn.2095-3259.2026.03.002

子痫前期及其并发症

子痫前期的降压治疗
洪凡, 王志坚()   
  1. 510515 广州医科大学附属第三医院妇产科 广东省产科重大疾病重点实验室 广东省妇产疾病临床医学研究中心 粤港澳母胎医学高校联合实验室
  • 收稿日期:2026-05-15 出版日期:2026-08-18
  • 通信作者: 王志坚

Antihypertensive treatment for preeclampsia

Fan Hong, Zhijian Wang()   

  • Received:2026-05-15 Published:2026-08-18
  • Corresponding author: Zhijian Wang
引用本文:

洪凡, 王志坚. 子痫前期的降压治疗[J/OL]. 中华产科急救电子杂志, 2026, 15(03): 134-140.

Fan Hong, Zhijian Wang. Antihypertensive treatment for preeclampsia[J/OL]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2026, 15(03): 134-140.

子痫前期是导致孕产妇及围产儿不良结局的主要原因之一,降压治疗旨在降低母体脑卒中、心力衰竭、肺水肿、肾损伤和子痫等严重并发症风险,同时避免血压下降过快影响子宫胎盘灌注。本文围绕子痫前期的治疗目标、启动时机、目标血压、常用药物,以及急性重度高血压处理、特殊临床情境和主要争议进行论述,强调全程、平稳、个体化管理。

Preeclampsia (PE) is one of the leading cause of adverse maternal and perinatal outcomes. Antihypertensive treatment aims to reduce serious maternal complications such as maternal stroke, heart failure, pulmonary edema, renal injury, and eclampsia, while avoiding an excessively rapid decline in blood pressure that may compromise uteroplacental perfusion. This review addresses the therapeutic targets, timing of initiation, blood pressure goals and commonly used antihypertensive agents in the management of PE, and also discusses the management of acute severe hypertension, special clinical scenarios, and major controversies, emphasizing the importance of continuous, stable, and individualized blood pressure management.

表1 不同指南/共识降压启动阈值与目标血压的比较
表2 子痫前期常用降压药物比较
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