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Chinese Journal of Obstetric Emergency(Electronic Edition) ›› 2012, Vol. 01 ›› Issue (02): 122-125. doi: 10.3877/cma.j.issn.2095-3259.2012.02.012

Special Issue:

• Original Article • Previous Articles     Next Articles

Amyotrophic lateral sclerosis with pregnancy: a case report and literature review

Han-qing CHEN1, Su-hua ZOU1, Zi-lian WANG1,(), Li-nan XU1, Cheng ZHANG2, Jian-bo YANG1, Jian CAI1, Run-cai LIANG1   

  1. 1. Department of Obstetrics and Gynecology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China
  • Received:2012-09-30 Online:2012-11-18 Published:2012-11-18
  • Contact: Zi-lian WANG
  • About author:
    Corresponding author: WANG Zi-lian, Email:

Abstract:

Objective

To review and summarize the clinical features and treatment of amyotrophic lateral sclerosis in the pregnant women.

Methods

To studies the clinical manifestation, treatment and the outcome of 1 pregnancy woman with amyotrophic lateral sclerosis in the First Affiliated Hospital of Sun Yat-sen University and previous 13 literature reports.

Results

There were 14 cases of amyotrophic lateral sclerosis during pregnancy and 16 times deliveries. For clinical manifestation, 6 cases had respiratory insufficiency, 4 cases had weakness of limbs, and 3 cases died of respiratory failure after delivery. For the outcome of delivery, 6 cases were premature deliveries, 5 cases were term deliveries, and 1 case was therapeutic abortion. No cases died of obstetric complications.

Conclusions

Respiratory failure is the main cause of maternal mortality in pregnant women with amyotrophic lateral sclerosis. Multidisciplinary cooperation closed monitoring and treatments of complications in time are necessary in perinatal period.

Key words: Amyotrophic lateral sclerosis, Pregnancy outcome, Case reports

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