Prenatal screening and prenatal diagnosis of chromosomal abnormalities in twin pregnancy

doi:10.3877/cma.j.issn.2095-3259.2019.01.005

Abstract

Abstract:

The risk of fetal malformation and chromosomal abnormalities in twin pregnancy is higher than that in single pregnancy. In recent years, the incidence of twin pregnancies and the number of pregnant women with advanced age are increasing, which makes the prenatal screening and prenatal diagnosis to be very important. In first trimester, nuchal translucency (NT) ultrasound screening is an important means, and serological screening alone is not recommended. In second trimester, ultrasound structure screening has certain significance for detecting fetal structural abnormalities. With the development of non-invasive prenatal genetic testing technology, it is of great significance in reducing the risk of invasive prenatal diagnosis. However, due to the current lack of clinical evidence, non-invasive genetic testing for twin pregnancy still requires caution.

Key words: Pregnancy, twin, Aneuploidy, Prenatal diagnosis

Xiaoling Guo. Prenatal screening and prenatal diagnosis of chromosomal abnormalities in twin pregnancy[J]. Chinese Journal of Obstetric Emergency(Electronic Edition), 2019, 08(01): 18-21.

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